Kohezin

Hromatidni kohezioni protein 1
Kohezinski kompleks se sastoji od
SCC1 i SMC1 proteina.[1]
Identifikatori
SimbolMCD1
Alt. simboliPDS3, RHC21, SCC1
Entrez851561
PDB1W1W
UniProtQ12158
Kohezinska podjedinica SCC3
Identifikatori
SimbolIRR1
Alt. simboliSCC3
Entrez854786
UniProtP40541
Strukturno održavanje hromozomskog proteina 1
Identifikatori
SimbolSMC1
Alt. simboliCHL10
Entrez850540
PDB1W1W
UniProtP32908
Strukturno održavanje hromozomskog proteina 3
Identifikatori
SimbolSMC3
Alt. simboliJ1049
Entrez853371
UniProtP47037

Kohesin je proteinski kompleks koji reguliše separaciju hromatida tokom ćelijske deobe, bilo mitoze ili mejoze.[2][3][4]

Reference

  1. ^ PDB: 1W1W​; Haering CH, Schoffnegger D, Nishino T, Helmhart W, Nasmyth K, Löwe J (2004). „Structure and stability of cohesin's Smc1-kleisin interaction”. Mol. Cell. 15 (6): 951—64. PMID 15383284. doi:10.1016/j.molcel.2004.08.030. 
  2. ^ Michaelis C, Ciosk R, Nasmyth K (1997). „Cohesins: chromosomal proteins that prevent premature separation of sister chromatids”. Cell. 91 (1): 35—45. PMID 9335333. doi:10.1016/S0092-8674(01)80007-6. 
  3. ^ Guacci V, Koshland D, Strunnikov A (1997). „A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae”. Cell. 91 (1): 47—57. PMC 2670185 Слободан приступ. PMID 9335334. doi:10.1016/S0092-8674(01)80008-8. 
  4. ^ Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K (1999). „Yeast Cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication”. Genes Dev. 13 (3): 320—33. PMC 316435 Слободан приступ. PMID 9990856. doi:10.1101/gad.13.3.320. 

Literatura

  • Michaelis C, Ciosk R, Nasmyth K (1997). „Cohesins: chromosomal proteins that prevent premature separation of sister chromatids”. Cell. 91 (1): 35—45. PMID 9335333. doi:10.1016/S0092-8674(01)80007-6. 
  • Guacci V, Koshland D, Strunnikov A (1997). „A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae”. Cell. 91 (1): 47—57. PMC 2670185 Слободан приступ. PMID 9335334. doi:10.1016/S0092-8674(01)80008-8. 
  • Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K (1999). „Yeast Cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication”. Genes Dev. 13 (3): 320—33. PMC 316435 Слободан приступ. PMID 9990856. doi:10.1101/gad.13.3.320. 
  • Uhlmann F, Lottspeich F, Nasmyth K (1999). „Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1”. Nature. 400 (6739): 37—42. PMID 10403247. doi:10.1038/21831. 

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Spoljašnje veze

  • cohesin на US National Library of Medicine Medical Subject Headings (MeSH)