CAV1 |
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識別子 |
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記号 | CAV1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, Caveolin 1 |
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外部ID | OMIM: 601047 MGI: 102709 HomoloGene: 1330 GeneCards: CAV1 |
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遺伝子オントロジー |
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分子機能 | • protein-macromolecule adaptor activity • transmembrane transporter binding • 構造分子活性 • 受容体結合 • nitric-oxide synthase binding • patched binding • 酵素結合 • peptidase activator activity • 血漿タンパク結合 • molecular adaptor activity • プロテインキナーゼ結合 • ATPase binding • cholesterol binding • inward rectifier potassium channel inhibitor activity • identical protein binding • protein heterodimerization activity • protein-containing complex binding
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細胞の構成要素 | • endocytic vesicle membrane • エンドソーム • 膜 • 焦点接着 • VCP-NPL4-UFD1 AAA ATPase complex • perinuclear region of cytoplasm • カベオラ • 繊毛 • apical plasma membrane • 小胞体 • 脂質ラフト • integral component of membrane • ゴルジ体 • early endosome membrane • 細胞膜 • 細胞内 • 細胞皮質 • endoplasmic reticulum membrane • ゴルジ膜 • integral component of plasma membrane • acrosomal membrane • basolateral plasma membrane • cytoplasmic vesicle • 脂肪滴 • 細胞質 • 高分子複合体 • 筋鞘
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生物学的プロセス | • caveolin-mediated endocytosis • positive regulation of calcium ion transport into cytosol • 血管収縮 • response to progesterone • negative regulation of protein binding • regulation of peptidase activity • protein localization to plasma membrane raft • 乳房発達 • 脈管形成 • negative regulation of pinocytosis • response to ischemia • 血管新生 • apoptotic signaling pathway • positive regulation of extrinsic apoptotic signaling pathway • cholesterol homeostasis • triglyceride metabolic process • negative regulation of canonical Wnt signaling pathway • calcium ion transport • negative regulation of cell population proliferation • cellular response to transforming growth factor beta stimulus • positive regulation of toll-like receptor 3 signaling pathway • regulation of cytosolic calcium ion concentration • regulation of smooth muscle contraction • vesicle organization • negative regulation of peptidyl-tyrosine autophosphorylation • regulation of cardiac muscle cell action potential involved in regulation of contraction • negative regulation of transforming growth factor beta receptor signaling pathway • protein localization to basolateral plasma membrane • receptor internalization involved in canonical Wnt signaling pathway • regulation of membrane repolarization during action potential • positive regulation of peptidyl-serine phosphorylation • negative regulation of protein tyrosine kinase activity • regulation of entry of bacterium into host cell • negative regulation of MAP kinase activity • positive regulation of vasoconstriction • negative regulation of potassium ion transmembrane transport • 授乳 • receptor-mediated endocytosis of virus by host cell • regulation of blood coagulation • regulation of ventricular cardiac muscle cell action potential • protein homooligomerization • viral process • positive regulation of intrinsic apoptotic signaling pathway • negative regulation of receptor signaling pathway via JAK-STAT • mammary gland involution • calcium ion homeostasis • negative regulation of necroptotic process • regulation of the force of heart contraction • lipid storage • nitric oxide homeostasis • 膜脱分極 • negative regulation of cytokine-mediated signaling pathway • cellular calcium ion homeostasis • negative regulation of transcription by RNA polymerase II • response to estrogen • response to calcium ion • regulation of fatty acid metabolic process • cellular response to exogenous dsRNA • negative regulation of MAPK cascade • regulation of ruffle assembly • positive regulation of protein binding • positive regulation of protein ubiquitination • negative regulation of anoikis • leukocyte migration • タンパク質局在化 • positive regulation of cell adhesion molecule production • 低酸素症への反応 • negative regulation of nitric-oxide synthase activity • 細菌への反応 • caveola assembly • cellular response to hyperoxia • cholesterol transport • cellular response to starvation • T cell costimulation • regulation of nitric-oxide synthase activity • receptor internalization • positive regulation of peptidase activity • positive regulation of ER-associated ubiquitin-dependent protein catabolic process • negative regulation of endothelial cell proliferation • negative regulation of BMP signaling pathway • negative regulation of protein ubiquitination • cellular response to peptide hormone stimulus • positive regulation of gene expression • negative regulation of nitric oxide biosynthetic process • angiotensin-activated signaling pathway involved in heart process • protein complex oligomerization • negative regulation of peptidyl-serine phosphorylation • posttranscriptional regulation of gene expression • positive regulation of gap junction assembly • maintenance of protein location in cell • negative regulation of signal transduction • regulation of the force of heart contraction by chemical signal • regulation of cell communication by electrical coupling involved in cardiac conduction • regulation of heart rate by cardiac conduction • negative regulation of epithelial cell differentiation • skeletal muscle tissue development • beta-catenin destruction complex disassembly • positive regulation of catalytic activity • positive regulation of canonical Wnt signaling pathway • negative regulation of tyrosine phosphorylation of STAT protein • negative regulation of inward rectifier potassium channel activity • 細胞分化 • positive regulation of cell migration • positive regulation of cold-induced thermogenesis • positive regulation of NF-kappaB transcription factor activity
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出典:Amigo / QuickGO |
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オルソログ |
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種 | ヒト | マウス |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001753 NM_001172895 NM_001172896 NM_001172897 |
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RefSeq (タンパク質) | |
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NP_001166366 NP_001166367 NP_001166368 NP_001744 |
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場所 (UCSC) | Chr 7: 116.52 – 116.56 Mb | Chr 7: 17.31 – 17.34 Mb |
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PubMed検索 | [3] | [4] |
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ウィキデータ |
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