ZNF408

Protein-coding gene in the species Homo sapiens
ZNF408
Identifiers
AliasesZNF408, EVR6, RP72, zinc finger protein 408
External IDsOMIM: 616454; MGI: 2685857; HomoloGene: 11687; GeneCards: ZNF408; OMA:ZNF408 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for ZNF408
Genomic location for ZNF408
Band11p11.2Start46,701,030 bp[1]
End46,705,912 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for ZNF408
Genomic location for ZNF408
Band2|2 E1Start91,474,014 bp[2]
End91,480,136 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • endothelial cell

  • tendon of biceps brachii

  • granulocyte

  • amniotic fluid

  • right lobe of liver

  • mucosa of transverse colon

  • gonad

  • thymus

  • parotid gland

  • sural nerve
Top expressed in
  • otic vesicle

  • granulocyte

  • ascending aorta

  • otolith organ

  • genital tubercle

  • utricle

  • cumulus cell

  • tail of embryo

  • aortic valve

  • supraoptic nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • protein binding
  • metal ion binding
  • identical protein binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79797

381410

Ensembl

ENSG00000175213

ENSMUSG00000075040

UniProt

Q9H9D4

n/a

RefSeq (mRNA)

NM_024741
NM_001184751

NM_001033451
NM_001347175

RefSeq (protein)

NP_001171680
NP_079017

n/a

Location (UCSC)Chr 11: 46.7 – 46.71 MbChr 2: 91.47 – 91.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 408 is a protein that in humans is encoded by the ZNF408 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175213 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075040 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zinc finger protein 408".

Further reading

  • Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H (February 2009). "Protein microarray analysis identifies human cellular prion protein interactors". Neuropathology and Applied Neurobiology. 35 (1): 16–35. doi:10.1111/j.1365-2990.2008.00947.x. PMID 18482256. S2CID 32299311.
  • Gao J, Li WX, Feng SQ, Yuan YS, Wan DF, Han W, Yu Y (April 2008). "A protein-protein interaction network of transcription factors acting during liver cell proliferation". Genomics. 91 (4): 347–55. doi:10.1016/j.ygeno.2007.12.007. PMID 18255255.
  • Rivadeneira F, Styrkársdottir U, Estrada K, Halldórsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, Kong A, Karasik D, van Meurs JB, Oostra B, Pastinen T, Pols HA, Sigurdsson G, Soranzo N, Thorleifsson G, Thorsteinsdottir U, Williams FM, Wilson SG, Zhou Y, Ralston SH, van Duijn CM, Spector T, Kiel DP, Stefansson K, Ioannidis JP, Uitterlinden AG (November 2009). "Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies". Nature Genetics. 41 (11): 1199–206. doi:10.1038/ng.446. PMC 2783489. PMID 19801982.
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