TRAPPC4

Protein-coding gene in the species Homo sapiens
TRAPPC4
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2J3T, 2JSN, 2ZMV

Identifiers
AliasesTRAPPC4, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23, CGI-104, trafficking protein particle complex 4, NEDESBA, trafficking protein particle complex subunit 4
External IDsOMIM: 610971; MGI: 1926211; HomoloGene: 105453; GeneCards: TRAPPC4; OMA:TRAPPC4 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for TRAPPC4
Genomic location for TRAPPC4
Band11q23.3Start119,018,763 bp[1]
End119,025,454 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for TRAPPC4
Genomic location for TRAPPC4
Band9|9 A5.2Start44,314,995 bp[2]
End44,318,897 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • islet of Langerhans

  • anterior pituitary

  • right testis

  • left testis

  • stromal cell of endometrium

  • ganglionic eminence

  • right adrenal gland

  • left adrenal gland

  • left adrenal cortex

  • human kidney
Top expressed in
  • medial ganglionic eminence

  • right kidney

  • ventricular zone

  • neural tube

  • morula

  • otic placode

  • granulocyte

  • facial motor nucleus

  • dentate gyrus of hippocampal formation granule cell

  • embryo
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • cytosol
  • Golgi apparatus
  • synaptic vesicle
  • synapse
  • dendrite
  • endoplasmic reticulum
  • Golgi stack
  • Golgi membrane
  • TRAPP complex
Biological process
  • dendrite development
  • COPII vesicle coating
  • vesicle-mediated transport
  • endoplasmic reticulum to Golgi vesicle-mediated transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51399

60409

Ensembl

ENSG00000280495
ENSG00000196655

ENSMUSG00000032112

UniProt

Q9Y296

Q9ES56

RefSeq (mRNA)
NM_016146
NM_001318486
NM_001318488
NM_001318489
NM_001318490

NM_001318492
NM_001318494

NM_021789

RefSeq (protein)
NP_001305415
NP_001305417
NP_001305418
NP_001305419
NP_001305421

NP_001305423
NP_057230

NP_068561

Location (UCSC)Chr 11: 119.02 – 119.03 MbChr 9: 44.31 – 44.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Trafficking protein particle complex subunit 4 is a protein that in humans is encoded by the TRAPPC4 gene.[5][6]

References

  1. ^ a b c ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032112 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  6. ^ "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  • Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1): 53–68. doi:10.1083/jcb.151.1.53. PMC 2189810. PMID 11018053.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • v
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  • 2j3t: THE CRYSTAL STRUCTURE OF THE BET3-TRS33-BET5-TRS23 COMPLEX.
    2j3t: THE CRYSTAL STRUCTURE OF THE BET3-TRS33-BET5-TRS23 COMPLEX.


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