TRAFD1

Protein-coding gene in the species Homo sapiens
TRAFD1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2D9K

Identifiers
AliasesTRAFD1, FLN29, TRAF-type zinc finger domain containing 1
External IDsOMIM: 613197; MGI: 1923551; HomoloGene: 31399; GeneCards: TRAFD1; OMA:TRAFD1 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for TRAFD1
Genomic location for TRAFD1
Band12q24.13Start112,125,538 bp[1]
End112,153,604 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for TRAFD1
Genomic location for TRAFD1
Band5|5 FStart121,509,788 bp[2]
End121,523,695 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • monocyte

  • granulocyte

  • Achilles tendon

  • muscle layer of sigmoid colon

  • islet of Langerhans

  • skin of leg

  • blood

  • skin of abdomen

  • ganglionic eminence
Top expressed in
  • spermatocyte

  • neural layer of retina

  • spermatid

  • zygote

  • ascending aorta

  • secondary oocyte

  • aortic valve

  • seminiferous tubule

  • Rostral migratory stream

  • lens
More reference expression data
BioGPS


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10906

231712

Ensembl

ENSG00000135148

ENSMUSG00000042726

UniProt

O14545

Q3UDK1

RefSeq (mRNA)

NM_006700
NM_001143906

NM_001163470
NM_172275
NM_001359947

RefSeq (protein)

NP_001137378
NP_006691

NP_001156942
NP_758479
NP_001346876

Location (UCSC)Chr 12: 112.13 – 112.15 MbChr 5: 121.51 – 121.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TRAF-type zinc finger domain-containing protein 1 is a protein that in humans is encoded by the TRAFD1 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135148 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042726 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: TRAFD1 TRAF-type zinc finger domain containing 1".

Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Mashima R, Saeki K, Aki D, et al. (2006). "FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling". J. Biol. Chem. 280 (50): 41289–97. doi:10.1074/jbc.M508221200. PMID 16221674.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • v
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  • 2d9k: Solution structure of the zf-TRAF domain of FLN29 gene product
    2d9k: Solution structure of the zf-TRAF domain of FLN29 gene product