TESPA1

Protein-coding gene in the species Homo sapiens
TESPA1
Identifiers
AliasesTESPA1, KIAA0748, HSPC257, thymocyte expressed, positive selection associated 1
External IDsOMIM: 615664; MGI: 1914846; HomoloGene: 106645; GeneCards: TESPA1; OMA:TESPA1 - orthologs
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[1]
Chromosome 10 (mouse)
Genomic location for TESPA1
Genomic location for TESPA1
Band10|10 D3Start130,158,739 bp[1]
End130,199,980 bp[1]
Gene ontology
Molecular function
  • signaling receptor binding
Cellular component
  • COP9 signalosome
  • endoplasmic reticulum membrane
  • endoplasmic reticulum
  • membrane
  • cytoplasm
Biological process
  • COP9 signalosome assembly
  • positive regulation of T cell differentiation in thymus
  • positive regulation of T cell receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9840

67596

Ensembl

ENSG00000135426

ENSMUSG00000034833

UniProt

A2RU30
E9PIT9

Q3U132

RefSeq (mRNA)

NM_001098815
NM_001136030
NM_001261844
NM_014796

NM_183264

RefSeq (protein)
NP_001092285
NP_001129502
NP_001248773
NP_055611
NP_001338077

NP_001338078
NP_001338079
NP_001338080
NP_001338081
NP_001338082
NP_001338083
NP_001338084

NP_899087

Location (UCSC)n/aChr 10: 130.16 – 130.2 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Thymocyte expressed, positive selection associated 1 is a protein that in humans is encoded by the TESPA1 gene.[4]

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034833 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Entrez Gene: Thymocyte expressed, positive selection associated 1".

Further reading

  • Fujimoto T, Matsuzaki H, Tanaka M, Shirasawa S (April 2013). "Tespa1 protein is phosphorylated in response to store-operated calcium entry". Biochemical and Biophysical Research Communications. 434 (1): 162–5. doi:10.1016/j.bbrc.2013.02.128. PMID 23541577.
  • Matsuzaki H, Fujimoto T, Tanaka M, Shirasawa S (April 2013). "Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux". Biochemical and Biophysical Research Communications. 433 (3): 322–6. doi:10.1016/j.bbrc.2013.02.099. PMID 23501103.
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