Phosalone
Names | |
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Preferred IUPAC name S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl phosphorodithioate | |
Other names Zolone | |
Identifiers | |
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3D model (JSmol) |
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ChEBI |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.017.270 |
KEGG |
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PubChem CID |
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UNII |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C12H15ClNO4PS2 |
Molar mass | 367.80 g·mol−1 |
Appearance | Colorless crystalline |
Odor | garlic |
Density | 1.39 g cm−3 |
Melting point | 47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K) |
Solubility in water | 3.05 mg/L |
Solubility | many organic solvents |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration in December 2006.
The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.[1]。It is a weak acetylcholinesterase inhibitor.[2] It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.[3] It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.[2] It is harmful especially to water creatures.
References
- ^ 製品安全データシート(安全衛生情報センター) Archived 2014-10-25 at the Wayback Machine
- ^ a b "国際化学物質安全性カード". Archived from the original on 2012-12-11. Retrieved 2012-09-06.
- ^ 植村振作・河村宏・辻万千子・冨田重行・前田静夫著 (2002). 農薬毒性の事典 改訂版. 三省堂. ISBN 978-4385356044.
External links
- Phosalone Fact Sheet
- EPA Webpage on Phosolone
- Phosalone in the Pesticide Properties DataBase (PPDB)
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