PUS7L

Protein-coding gene in the species Homo sapiens
PUS7L
Identifiers
AliasesPUS7L, pseudouridylate synthase 7 like, pseudouridine synthase 7 like
External IDsMGI: 1926145; HomoloGene: 12842; GeneCards: PUS7L; OMA:PUS7L - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for PUS7L
Genomic location for PUS7L
Band12q12Start43,718,992 bp[1]
End43,758,793 bp[1]
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[2]
Chromosome 15 (mouse)
Genomic location for PUS7L
Genomic location for PUS7L
Band15|15 E3Start94,420,569 bp[2]
End94,441,428 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • epithelium of colon

  • secondary oocyte

  • testicle

  • tibia

  • corpus epididymis

  • corpus callosum

  • gonad

  • tonsil

  • bone marrow cells
Top expressed in
  • otic vesicle

  • medullary collecting duct

  • Paneth cell

  • ureter

  • condyle

  • primitive streak

  • trigeminal ganglion

  • endothelial cell of lymphatic vessel

  • lumbar spinal ganglion

  • fossa
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • pseudouridine synthase activity
  • protein binding
  • isomerase activity
  • RNA binding
Cellular component
  • nucleus
Biological process
  • RNA modification
  • pseudouridine synthesis
  • tRNA processing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83448

78895

Ensembl

ENSG00000129317

ENSMUSG00000033356

UniProt

Q9H0K6

Q8CE46

RefSeq (mRNA)

NM_001098614
NM_001098615
NM_001271826
NM_031292

NM_172437

RefSeq (protein)

NP_001092084
NP_001092085
NP_001258755
NP_112582

NP_766025

Location (UCSC)Chr 12: 43.72 – 43.76 MbChr 15: 94.42 – 94.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000129317 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033356 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ "Entrez Gene: PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


  • v
  • t
  • e