Gadolinium(III) oxide
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Other names gadolinium sesquioxide, gadolinium trioxide | |
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ECHA InfoCard | 100.031.861 ![]() |
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InChI
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Properties | |
Chemical formula | Gd2O3 |
Molar mass | 362.50 g/mol |
Appearance | white odorless powder |
Density | 7.07 g/cm3 [1] |
Melting point | 2,420 °C (4,390 °F; 2,690 K) |
Solubility in water | insoluble |
Solubility product (Ksp) | 1.8×10−23 |
Solubility | soluble in acid |
Magnetic susceptibility (χ) | +53,200·10−6 cm3/mol |
Structure | |
Crystal structure | cubic, cI80, Monoclinic |
Ia-3, No. 206, C2/m, No. 12 | |
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Warning | |
H319, H410 | |
P264, P273, P280, P305+P351+P338, P337+P313, P391, P501 | |
Safety data sheet (SDS) | External MSDS |
Related compounds | |
Other anions | Gadolinium(III) chloride |
Other cations | Europium(III) oxide, Terbium(III) oxide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ![]() ![]() ![]() Infobox references |
Gadolinium(III) oxide (archaically gadolinia) is an inorganic compound with the formula Gd2O3. It is one of the most commonly available forms of the rare-earth element gadolinium, derivatives of which are potential contrast agents for magnetic resonance imaging.
Structure
![](http://upload.wikimedia.org/wikipedia/commons/thumb/7/70/Tl2O3structure.jpg/170px-Tl2O3structure.jpg)
![](http://upload.wikimedia.org/wikipedia/commons/thumb/0/05/Gd2O3structure.jpg/220px-Gd2O3structure.jpg)
Gadolinium oxide adopts two structures. The cubic (cI80, Ia3), No. 206) structure is similar to that of manganese(III) oxide and heavy trivalent lanthanide sesquioxides. The cubic structure features two types of gadolinium sites, each with a coordination number of 6 but with different coordination geometries. The second polymorph is monoclinic (Pearson symbol mS30, space group C2/m, No. 12).[2] At room temperature, the cubic structure is more stable. The phase change to the monoclinic structure takes place at 1200 °C. Above 2100 °C to the melting point at 2420 °C, a hexagonal phase dominates.[3]
Preparation and chemistry
Gadolinium oxide can be formed by thermal decomposition of the hydroxide, nitrate, carbonate, or oxalates.[4] Gadolinium oxide forms on the surface of gadolinium metal.
Gadolinium oxide is a rather basic oxide, indicated by its ready reaction with carbon dioxide to give carbonates. It dissolves readily in the common mineral acids with the complication that the oxalate, fluoride, sulfate and phosphate are very insoluble in water and may coat the grains of oxide, thereby preventing the complete dissolution.[5]
Nanoparticles of Gd2O3
Several methods are known for the synthesis of gadolinium oxide nanoparticles, mostly based on precipitation of the hydroxide by the reaction of gadolinium ions with hydroxide, followed by thermal dehydration to the oxide. The nanoparticles are always coated with a protective material to avoid the formation of larger polycrystalline aggregates.[6][7][8]
Nanoparticles of gadolinium oxide is a potential contrast agent for magnetic resonance imaging (MRI). A dextran-coated preparation of 20–40 nm sized gadolinium oxide particles had a relaxivity of 4.8 s−1mM−1 per gadolinium ion at 7.05 T (an unusually high field compared to the clinically used MRI scanners which mostly range from 0.5 to 3 T).[6] Smaller particles, between 2 and 7 nm, were tested as an MRI agent.[7][8]
References
- ^ Pradyot Patnaik. Handbook of Inorganic Chemicals. McGraw-Hill, 2002, ISBN 0-07-049439-8.
- ^ Wells, A.F. (1984) Structural Inorganic Chemistry 5th edition Oxford Science Publications. ISBN 0-19-855370-6.
- ^ Adachi, Gin-ya; Imanaka, Nobuhito (1998). "The Binary Rare Earth Oxides". Chemical Reviews. 98 (4): 1479–1514. doi:10.1021/cr940055h. PMID 11848940.
- ^ Cotton, S. (2006) Lanthanide and Actinide Chemistry Wiley ISBN 0-470-01006-1 p. 6
- ^ Yost, D.M, Russell, H. Jr., Garner, C.S. The Rare-Earth Elements and their Compounds, Wiley, 1947.
- ^ a b McDonald, M; Watkin, K (2006). "Investigations into the Physicochemical Properties of Dextran Small Particulate Gadolinium Oxide Nanoparticles". Academic Radiology. 13 (4): 421–27. doi:10.1016/j.acra.2005.11.005. PMID 16554221.
- ^ a b Bridot, Jean-Luc; Faure, Anne-Charlotte; Laurent, Sophie; Rivière, Charlotte; Billotey, Claire; Hiba, Bassem; Janier, Marc; Josserand, VéRonique; et al. (2007). "Hybrid Gadolinium Oxide Nanoparticles: Multimodal Contrast Agents for in Vivo Imaging". Journal of the American Chemical Society. 129 (16): 5076–84. doi:10.1021/ja068356j. PMID 17397154.
- ^ a b Engström, Maria; Klasson, Anna; Pedersen, Henrik; Vahlberg, Cecilia; Käll, Per-Olov; Uvdal, Kajsa (2006). "High proton relaxivity for gadolinium oxide nanoparticles". Magnetic Resonance Materials in Physics, Biology and Medicine. 19 (4): 180–86. doi:10.1007/s10334-006-0039-x. PMID 16909260. S2CID 23259790.
- v
- t
- e
- Antimony tetroxide (Sb2O4)
- Boron suboxide (B12O2)
- Carbon suboxide (C3O2)
- Chlorine perchlorate (Cl2O4)
- Chloryl perchlorate (Cl2O6)
- Cobalt(II,III) oxide (Co3O4)
- Dichlorine pentoxide (Cl2O5)
- Iron(II,III) oxide (Fe3O4)
- Lead(II,IV) oxide (Pb3O4)
- Manganese(II,III) oxide (Mn3O4)
- Mellitic anhydride (C12O9)
- Praseodymium(III,IV) oxide (Pr6O11)
- Silver(I,III) oxide (Ag2O2)
- Terbium(III,IV) oxide (Tb4O7)
- Tribromine octoxide (Br3O8)
- Triuranium octoxide (U3O8)
- Aluminium(I) oxide (Al2O)
- Copper(I) oxide (Cu2O)
- Caesium monoxide (Cs2O)
- Dicarbon monoxide (C2O)
- Dichlorine monoxide (Cl2O)
- Gallium(I) oxide (Ga2O)
- Iodine(I) oxide (I2O)
- Lithium oxide (Li2O)
- Mercury(I) oxide (Hg2O)
- Nitrous oxide (N2O)
- Potassium oxide (K2O)
- Rubidium oxide (Rb2O)
- Silver oxide (Ag2O)
- Thallium(I) oxide (Tl2O)
- Sodium oxide (Na2O)
- Water (hydrogen oxide) (H2O)
- Aluminium(II) oxide (AlO)
- Barium oxide (BaO)
- Berkelium monoxide (BkO)
- Beryllium oxide (BeO)
- Bromine monoxide (BrO)
- Cadmium oxide (CdO)
- Calcium oxide (CaO)
- Carbon monoxide (CO)
- Chlorine monoxide (ClO)
- Chromium(II) oxide (CrO)
- Cobalt(II) oxide (CoO)
- Copper(II) oxide (CuO)
- Dinitrogen dioxide (N2O2)
- Europium(II) oxide (EuO)
- Germanium monoxide (GeO)
- Iron(II) oxide (FeO)
- Iodine monoxide (IO)
- Lead(II) oxide (PbO)
- Magnesium oxide (MgO)
- Manganese(II) oxide (MnO)
- Mercury(II) oxide (HgO)
- Nickel(II) oxide (NiO)
- Nitric oxide (NO)
- Palladium(II) oxide (PdO)
- Phosphorus monoxide (PO)
- Polonium monoxide (PoO)
- Protactinium monoxide (PaO)
- Radium oxide (RaO)
- Silicon monoxide (SiO)
- Strontium oxide (SrO)
- Sulfur monoxide (SO)
- Disulfur dioxide (S2O2)
- Thorium monoxide (ThO)
- Tin(II) oxide (SnO)
- Titanium(II) oxide (TiO)
- Vanadium(II) oxide (VO)
- Yttrium(II) oxide (YO)
- Zinc oxide (ZnO)
- Actinium(III) oxide (Ac2O3)
- Aluminium oxide (Al2O3)
- Americium(III) oxide (Am2O3)
- Antimony trioxide (Sb2O3)
- Arsenic trioxide (As2O3)
- Berkelium(III) oxide (Bk2O3)
- Bismuth(III) oxide (Bi2O3)
- Boron trioxide (B2O3)
- Caesium sesquioxide (Cs2O3)
- Californium(III) oxide (Cf2O3)
- Cerium(III) oxide (Ce2O3)
- Chromium(III) oxide (Cr2O3)
- Cobalt(III) oxide (Co2O3)
- Dinitrogen trioxide (N2O3)
- Dysprosium(III) oxide (Dy2O3)
- Einsteinium(III) oxide (Es2O3)
- Erbium(III) oxide (Er2O3)
- Europium(III) oxide (Eu2O3)
- Gadolinium(III) oxide (Gd2O3)
- Gallium(III) oxide (Ga2O3)
- Gold(III) oxide (Au2O3)
- Holmium(III) oxide (Ho2O3)
- Indium(III) oxide (In2O3)
- Iron(III) oxide (Fe2O3)
- Lanthanum oxide (La2O3)
- Lutetium(III) oxide (Lu2O3)
- Manganese(III) oxide (Mn2O3)
- Neodymium(III) oxide (Nd2O3)
- Nickel(III) oxide (Ni2O3)
- Phosphorus trioxide (P4O6)
- Praseodymium(III) oxide (Pr2O3)
- Promethium(III) oxide (Pm2O3)
- Rhodium(III) oxide (Rh2O3)
- Samarium(III) oxide (Sm2O3)
- Scandium oxide (Sc2O3)
- Terbium(III) oxide (Tb2O3)
- Thallium(III) oxide (Tl2O3)
- Thulium(III) oxide (Tm2O3)
- Titanium(III) oxide (Ti2O3)
- Tungsten(III) oxide (W2O3)
- Vanadium(III) oxide (V2O3)
- Ytterbium(III) oxide (Yb2O3)
- Yttrium(III) oxide (Y2O3)
- Americium dioxide (AmO2)
- Berkelium(IV) oxide (BkO2)
- Bromine dioxide (BrO2)
- Californium dioxide (CfO2)
- Carbon dioxide (CO2)
- Carbon trioxide (CO3)
- Cerium(IV) oxide (CeO2)
- Chlorine dioxide (ClO2)
- Chromium(IV) oxide (CrO2)
- Curium(IV) oxide (CmO2)
- Dinitrogen tetroxide (N2O4)
- Germanium dioxide (GeO2)
- Iodine dioxide (IO2)
- Hafnium(IV) oxide (HfO2)
- Lead dioxide (PbO2)
- Manganese dioxide (MnO2)
- Neptunium(IV) oxide (NpO2)
- Nitrogen dioxide (NO2)
- Osmium dioxide (OsO2)
- Plutonium(IV) oxide (PuO2)
- Polonium dioxide (PoO2)
- Praseodymium(IV) oxide (PrO2)
- Protactinium(IV) oxide (PaO2)
- Rhodium(IV) oxide (RhO2)
- Ruthenium(IV) oxide (RuO2)
- Selenium dioxide (SeO2)
- Silicon dioxide (SiO2)
- Sulfur dioxide (SO2)
- Technetium(IV) oxide (TcO2)
- Tellurium dioxide (TeO2)
- Terbium(IV) oxide (TbO2)
- Thorium dioxide (ThO2)
- Tin dioxide (SnO2)
- Titanium dioxide (TiO2)
- Tungsten(IV) oxide (WO2)
- Uranium dioxide (UO2)
- Vanadium(IV) oxide (VO2)
- Zirconium dioxide (ZrO2)
- Antimony pentoxide (Sb2O5)
- Arsenic pentoxide (As2O5)
- Bismuth pentoxide (Bi2O5)
- Dinitrogen pentoxide (N2O5)
- Niobium pentoxide (Nb2O5)
- Phosphorus pentoxide (P2O5)
- Protactinium(V) oxide (Pa2O5)
- Tantalum pentoxide (Ta2O5)
- Vanadium(V) oxide (V2O5)
- Chromium trioxide (CrO3)
- Molybdenum trioxide (MoO3)
- Polonium trioxide (PoO3)
- Rhenium trioxide (ReO3)
- Selenium trioxide (SeO3)
- Sulfur trioxide (SO3)
- Tellurium trioxide (TeO3)
- Tungsten trioxide (WO3)
- Uranium trioxide (UO3)
- Xenon trioxide (XeO3)
- Dichlorine heptoxide (Cl2O7)
- Manganese heptoxide (Mn2O7)
- Rhenium(VII) oxide (Re2O7)
- Technetium(VII) oxide (Tc2O7)
- Iridium tetroxide (IrO4)
- Osmium tetroxide (OsO4)
- Ruthenium tetroxide (RuO4)
- Xenon tetroxide (XeO4)
- Hassium tetroxide (HsO4)