DYRK3 |
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Identifiers |
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Aliases | DYRK3, DYRK5, RED, REDK, hYAK3-2, dual specificity tyrosine phosphorylation regulated kinase 3 |
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External IDs | OMIM: 603497; MGI: 1330300; HomoloGene: 55762; GeneCards: DYRK3; OMA:DYRK3 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1q32.1 | Start | 206,635,536 bp[1] |
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End | 206,684,419 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 E4 | Start | 131,055,192 bp[2] |
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End | 131,066,077 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - beta cell
- left testis
- right testis
- male germ cell
- sperm
- vena cava
- cartilage tissue
- stromal cell of endometrium
- apex of heart
- mucosa of urinary bladder
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| Top expressed in | - seminiferous tubule
- spermatid
- fetal liver hematopoietic progenitor cell
- spermatocyte
- respiratory epithelium
- nasal epithelium
- olfactory epithelium
- parotid gland
- facial motor nucleus
- ventricular zone
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- protein kinase activity
- protein serine/threonine/tyrosine kinase activity
- protein tyrosine kinase activity
- nucleotide binding
- ATP binding
- magnesium ion binding
- metal ion binding
- kinase activity
- protein serine/threonine kinase activity
| Cellular component | - nucleus
- nucleoplasm
- cytosol
- intracellular membrane-bounded organelle
- cytoplasm
- cytoplasmic stress granule
- pericentriolar material
- microtubule organizing center
- cytoskeleton
- nuclear speck
| Biological process | - erythrocyte differentiation
- protein phosphorylation
- peptidyl-tyrosine phosphorylation
- phosphorylation
- stress granule disassembly
- negative regulation of apoptotic process
- negative regulation of DNA damage response, signal transduction by p53 class mediator
- regulation of cellular response to stress
- regulation of TORC1 signaling
- cell cycle
- nuclear speck organization
- cell division
- positive regulation of cell cycle G2/M phase transition
- organelle disassembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 206.64 – 206.68 Mb | Chr 1: 131.06 – 131.07 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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